Person:
Eens, Marcel

Profile Picture
Email Address
Birth Date
1994-10-22
Research Projects
Organizational Units
Job Title
Spokesperson Behavioural Ecology and Ecophysiology
Last Name
Eens
First Name
Marcel
Name

Search Results

Now showing 1 - 8 of 8
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Publication

TestTheses1

2018-05-17, Eens, M., Vercauteren, Marcel, De Wael, K., Anaesthesiology, Abdominal and Paediatric Surgery

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Publication

Dengue Human Infection Models Supporting Drug Development

2014-06-15, Plain text author, Plain text author 2, Eens, Marcel, Vercauteren, Marcel, Simmons, Cameron

Dengue is a arboviral infection that represents a major global health burden. There is an unmet need for effective dengue therapeutics to reduce symptoms, duration of illness and incidence of severe complications. Here, we consider the merits of a dengue human infection model (DHIM) for drug development. A DHIM could allow experimentally controlled studies of candidate therapeutics in preselected susceptible volunteers, potentially using smaller sample sizes than trials that recruited patients with dengue in an endemic country. In addition, the DHIM would assist the conduct of intensive pharmacokinetic and basic research investigations and aid in determining optimal drug dosage. Furthermore, a DHIM could help establish proof of concept that chemoprophylaxis against dengue is feasible. The key challenge in developing the DHIM for drug development is to ensure the model reliably replicates the typical clinical and laboratory features of naturally acquired, symptomatic dengue.

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Publication

TestTheses3

2018-05-17, Eens, Marcel, De Wael, Karolien, Anaesthesiology, Medicine and Health Sciences

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Publication

TestArticle1

, Vercauteren, Marcel, Abdominal and Paediatric Surgery, Eens, Marcel, Medicine and Health Sciences, De Wael, Karolien, Medicine and Health Sciences, Abdominal and Paediatric Surgery, Anaesthesiology

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Publication

TestArticle2

2018-05-17, Eens, Marcel, De Wael, Karolien, Medicine and Health Sciences, Anaesthesiology

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Publication

TestBook1

2018-05-17, Eens, Marc, Vercauteren, Marcel, De Wael, Karolien, Anaesthesiology, Abdominal and Paediatric Surgery

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Publication

TestBook2

2018-05-17, Eens, Marcel, Medicine and Health Sciences

No Thumbnail Available
Publication

TestTheses2

2018-05-17, Medicine and Health Sciences, Abdominal and Paediatric Surgery, Eens, Marcel, Vercauteren, Marcel, De Wael, Karolien, Abdominal and Paediatric Surgery