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Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health

dc.contributor.authorSimmons, Cameron
dc.date.accessioned2018-09-14T11:14:59Z
dc.date.available2015-11-24T00:15:29Z
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2015-02-09en_US
dc.date.available2018-09-14T11:14:59Z
dc.date.issued2015-10-15en_US
dc.description.abstractAedes albopictus is secondary to Aedes aegypti as a vector of dengue viruses (DENVs) in settings of endemicity, but it plays an important role in areas of dengue emergence. This study compared the susceptibility of these 2 species to DENV infection by performing 232 direct blood-feeding experiments on 118 viremic patients with dengue in Vietnam. Field-derived A. albopictus acquired DENV infections as readily as A. aegypti after blood feeding. Once infected, A. albopictus permitted higher concentrations of DENV RNA to accumulate in abdominal tissues, compared with A. aegypti. However, the odds of A. albopictus having infectious saliva were lower than the odds observed for A. aegypti (odds ratio, 0.70; 95% confidence interval, .52-.93). These results quantitate the susceptibility of A. albopictus to DENV infection and will assist parameterization of models for predicting disease risk in settings where A. albopictus is present.
dc.identifier.urihttps://demo7.dspace.org/handle/10673/142
dc.languageEnglishen_US
dc.titleComparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Healthen_US
dc.typeJournal Article
dspace.entity.typePublication
relation.isAuthorOfPublicationb1b2c768-bda1-448a-a073-fc541e8b24d9
relation.isAuthorOfPublication.latestForDiscoveryb1b2c768-bda1-448a-a073-fc541e8b24d9
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