Publication:
The Seroprevalence and Seroincidence of Enterovirus71 Infection in Infants and Children in Ho Chi Minh City, Viet Nam

dc.date.accessioned 2018-09-14T11:14:59Z
dc.date.available 2016-06-22T00:46:37Z
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2011-05-19 en_US
dc.date.available 2018-09-14T11:14:59Z
dc.date.issued 2011-07-12 en_US
dc.description.abstract Enterovirus 71 (EV71)-associated hand, foot and mouth disease has emerged as a serious public health problem in South East Asia over the last decade. To better understand the prevalence of EV71 infection, we determined EV71 seroprevalence and seroincidence amongst healthy infants and children in Ho Chi Minh City, Viet Nam. In a cohort of 200 newborns, 55% of cord blood samples contained EV71 neutralizing antibodies and these decayed to undetectable levels by 6 months of age in 98% of infants. The EV71 neutralizing antibody seroconversion rate was 5.6% in the first year and 14% in the second year of life. In children 5-15 yrs of age, seroprevalence of EV71 neutralizing antibodies was 84% and in cord blood it was 55%. Taken together, these data suggest EV71 force of infection is high and highlights the need for more research into its epidemiology and pathogenesis in high disease burden countries.
dc.identifier.uri https://demo7.dspace.org/handle/10673/149
dc.language English en_US
dc.title The Seroprevalence and Seroincidence of Enterovirus71 Infection in Infants and Children in Ho Chi Minh City, Viet Nam en_US
dc.type Journal Article
dspace.entity.type Publication
relation.isAuthorOfPublication b1b2c768-bda1-448a-a073-fc541e8b24d9
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