Host defences to Citrobacter rodentium Simmons, Cameron 2018-09-14T11:15:07Z 2017-07-05T04:51:50Z 2018-09-14T11:15:07Z 2003-04-01 en_US
dc.description.abstract Citrobacter rodentium is a natural non-invasive bacterial pathogen which infects the distal colon of mice. It uses the same molecular mechanisms of type III secretion as human enteropathogenic and enterohemorrhagic Escherichia coli to colonise the epithelial cells of the gut and is therefore an ideal model to study host-bacterial pathogen interactions in vivo. Infection elicits mucosal inflammation with similarities to inflammatory bowel disease, and so it is a readily accessible model to investigate the relationship between inflammation and anti-bacterial immunity in the gut.
dc.language English en_US
dc.title Host defences to Citrobacter rodentium en_US
dc.type Journal Article
dspace.entity.type Publication
relation.isAuthorOfPublication b1b2c768-bda1-448a-a073-fc541e8b24d9