Publication:
Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health

dc.contributor.author Simmons, Cameron
dc.date.accessioned 2018-09-14T11:14:59Z
dc.date.available 2015-11-24T00:15:29Z
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2015-02-09 en_US
dc.date.available 2018-09-14T11:14:59Z
dc.date.issued 2015-10-15 en_US
dc.description.abstract Aedes albopictus is secondary to Aedes aegypti as a vector of dengue viruses (DENVs) in settings of endemicity, but it plays an important role in areas of dengue emergence. This study compared the susceptibility of these 2 species to DENV infection by performing 232 direct blood-feeding experiments on 118 viremic patients with dengue in Vietnam. Field-derived A. albopictus acquired DENV infections as readily as A. aegypti after blood feeding. Once infected, A. albopictus permitted higher concentrations of DENV RNA to accumulate in abdominal tissues, compared with A. aegypti. However, the odds of A. albopictus having infectious saliva were lower than the odds observed for A. aegypti (odds ratio, 0.70; 95% confidence interval, .52-.93). These results quantitate the susceptibility of A. albopictus to DENV infection and will assist parameterization of models for predicting disease risk in settings where A. albopictus is present.
dc.identifier.uri https://demo7.dspace.org/handle/123456789/142
dc.language English en_US
dc.title Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health en_US
dc.type Journal Article
dspace.entity.type Publication
relation.isAuthorOfPublication b1b2c768-bda1-448a-a073-fc541e8b24d9
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